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Global Pharmaceutical Manufacturer Selects Perlast FDA Approved Seals


GlaxoSmithKline (GSK), one of the world's leading research-based pharmaceutical and healthcare companies manufacturing over 50 products within three business units: Steriles & Liquids, Topicals and Cephs.


GSK undertook a review of seals on equipment used on a single Topicals filling and packaging line. The review indicated that in some cases the dimensional accuracy of the seals could be improved and changes to the type of elastomer to better match the Topicals chemistry and cleaning processes could also extend the plant's production time before a seal change was needed.


PPE systematically checked all seals and recommended a switch to an alternative grade of FDA/USP class VI compliant FKM and the use of Perlast® FFKM, an elastomer developed specifically for pharmaceutical applications.


Improvements in part traceability and an increase in the production time between seals changes, compared with the more frequent seal changes before the review. Subsequently a further seven Topicals filling and packaging lines have been upgraded with the PPE seals.

How can we help? Contact our pharmaceutical and biomedical sealing experts to discuss your requirements, or start a discussion online.

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